LexisNexis Risk Solutions has introduced advanced deepfake detection and fraud prevention enhancements specifically for Epic MyChart, the widely used patient portal. The new capabilities use AI-driven voice and video biometrics, behavioral analysis, and real-time risk scoring to protect against sophisticated impersonation attacks addressing rising concerns over deepfake-enabled fraud targeting patient accounts, prescription requests, and protected health information.
Glimpse:
Launched on January 28, 2026, the LexisNexis solution integrates natively into Epic MyChart workflows to verify user identity during high-risk interactions (e.g., telehealth visits, prescription refills, record amendments, or account recovery). It combines liveness detection, voiceprint matching, facial recognition, behavioral biometrics (keystroke/mouse patterns), and device intelligence to block deepfake attempts with over 95% accuracy in early testing. The tool also flags suspicious activity patterns (e.g., unusual login locations, rapid prescription requests) for additional review, helping providers comply with HIPAA security rules while maintaining seamless patient access.
LexisNexis Risk Solutions has expanded its healthcare fraud and identity verification suite with new deepfake defense capabilities tailored for Epic MyChart, the patient portal used by millions through Epic-based health systems. The announcement, made on January 28, 2026, comes amid growing reports of deepfake technology being used to impersonate patients or providers in telehealth encounters, prescription fraud schemes, and account takeovers threats that traditional authentication methods (passwords, SMS OTP) increasingly fail to stop.
The solution deploys a multi-layered defense stack that operates seamlessly within Epic MyChart:
- Voice and video liveness detection — Analyzes micro-expressions, lip-sync, eye movement, and audio artifacts to distinguish real humans from deepfake-generated media in real time
- Biometric matching — Compares live voiceprint and facial features against previously enrolled profiles (enrolled during initial account setup or in-person verification)
- Behavioral biometrics — Monitors typing cadence, mouse movements, swipe patterns, and session behavior to detect anomalies indicative of account compromise
- Device and network intelligence — Flags logins from unfamiliar devices, locations, or IP ranges, triggering step-up authentication or temporary restrictions
- Risk-based authentication engine — Assigns dynamic risk scores to each interaction, escalating only high-risk actions (e.g., changing medications, requesting controlled substances, or amending records) for additional verification
The technology is designed to be frictionless for legitimate users most routine logins and low-risk actions require no extra steps while providing robust protection against impersonation and fraud. It is fully HIPAA-compliant, with end to end encryption, audit logging, and no storage of raw biometric data (only encrypted templates).
Early testing with select Epic customers has shown detection rates above 95% for known deepfake attacks, significant reduction in fraudulent prescription requests, and minimal impact on legitimate user experience. The solution also includes post-event forensics to support compliance investigations and law enforcement coordination when fraud is confirmed.
LexisNexis Healthcare Executive stated: “As deepfake technology becomes more accessible, patient portals like Epic MyChart are increasingly attractive targets. Our new capabilities provide the first line of defense against these sophisticated threats protecting PHI, preventing fraud, and preserving trust in digital care delivery.”
The integration is now available to Epic-based health systems through LexisNexis Risk Solutions’ healthcare fraud prevention suite, with rapid onboarding support for interested providers. The partnership reflects growing urgency among health systems to safeguard patient portals as telehealth, e-prescribing, and digital record access become standard.
“Deepfakes aren’t science fiction anymore they’re a real threat to patient safety and data integrity. By embedding advanced detection directly into MyChart workflows, we’re helping providers stay one step ahead of fraudsters while keeping care convenient and secure.”
By
HB Team

